ANTI-AGING EFFECT ON OCULAR TISSUES OF ANTIOXIDANT VEGETAL SUPPLEMENTS FROM ROMANIAN MARKET

References: 14th International Multidisciplinary Scientific GeoConference SGEM 2014, www.sgem.org, SGEM2014 Conference Proceedings, ISBN 978-619-7105-20-9 / ISSN 1314-2704, June 19-25, 2014, Book 6, Vol. 1, 225-230 pp

ABSTRACT
The aim of the paper is to reveal any differences of therapy response which
might be related to antioxidant activity of anti – aging vegetal supplement represented by tablets that contain active vegetal principles such as (Coleus forkohlii extract, omotaurina (a natural molecule extracted from certain varieties of seaweed, able to get to all body tissues, including the central nervous system, GABA and taurine like structures), magnesium, L-carnosine; vitamins (B2, B6, B1) and folic acid. For this reason we used 3 groups of 40 persons of each one divided after gender (males and females) and age (20 – over 65 years) and different affections (20 patients with myopia, 15 patients with macular degeneration, 5 patients with peripheral retinal degenerescence), from these 3 groups one was the control one. From the two experimental groups, one received daily 1 tablet, and the other one, received daily 2 tablets, both over one year. Clinical evaluation before and after the treatment of these vegetal supplements action was done by Amsler ophthalmologic test, visual acuity, visual field, ophthalmological examination for degenerescence maculopathy. For peripheral retinal degenerescence, clinical evaluation of the vegetal supplements action was done by visual acuity, visual field, ophthalmoscopic aspect of the retina and for myopia disease by refraction, visual acuity, visual field and ophthalmoscopic examination. The antioxidant activity of these different vegetal used supplements was determined by a photochemiluminescence method, based on the multiple acceleration of a natural reaction leading to the generation of a superoxide anion radical. The measured anti-oxidative capacity is then quantified by comparison with a standard substance used for calibration, Trolox as tocopherol analog using Photochem, Analytik Jena AG apparatus. The antioxidant capacity results show that after the treatment based on different vegetal active principles, some of visual parameters improved or at least remained the same compared to control group, without treatment.

Keywords: anti-aging effect, ocular tissue, vegetal supplement, antioxidant activity